There exists a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors from the dorsal horn to lower afferent suffering transmission and deliver analgesia. Thus, medicines like clonidine that target alpha-2 receptors can affect the transmission of discomfort. : linked to, served by, or out https://socialdummies.com/story4663207/the-2-minute-rule-for-onolidine