There's a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors during the dorsal horn to reduce afferent discomfort transmission and develop analgesia. Hence, medication like clonidine that concentrate on alpha-2 receptors can affect the transmission of pain. Jun 10, 2024 · If clonidine therapy https://colini582jwk9.wikijournalist.com/user