Making predictions about DNA methylation status on the sex-determining location with the initiation of sex chromosome divergence isn't straightforward, as regulation of gene expression by DNA methylation is usually advanced (Jaenisch and Chook 2003). For example, hypermethylation of promoter regions is associated with a transcriptionally repressed state. In distinction, https://badguy.cyou/news/domination/orlando_transexual_escort.html